Endocrine Abstracts

The epidemic nature of obesity/overweight throughout the developed and less-developed world suggests that major new influences are at play. Correct identification of these influences must precede discussion of what action can rationally be planned. The widespread failure to recognise that this problem concerns the whole population and not merely those with a BMI over the arbitrary normal level is a critical factor in appreciating the nature of the problem. The lack of efficacy...

The epidemic nature of obesity/overweight throughout the developed and less-developed world suggests that major new influences are at play. Correct identification of these influences must precede discussion of what action can rationally be planned. The widespread failure to recognise that this problem concerns the whole population and not merely those with a BMI over the arbitrary normal level is a critical factor in appreciating the nature of the problem. The lack of efficacy...

Background: It is well established that subclinical hypothyroidism (SCH) is associated with mild ventricular dysfunction and early cardiovascular disease (CVD), but it is unknown if there is an underlying defect in cardiac bio-energetic function.Objective: To quantify the cardiac phosphocreatine/ATP (PCr/ATP) ratio in SCH, compare with healthy controls (HC) and to measure the effect of 6 months of thyroxine treatment.Method: Cardia...

Introduction: Congenital adrenal hyperplasia (CAH) is an inherited disorder, most commonly caused by enzymatic deficiency of 21-hydroxylase (CYP21A2). The non-classic or late-onset form is one of the most common autosomal recessive diseases in women, but the diagnosis is only rarely made in men unless they happen to present with testicular or adrenal masses or infertility.Case report: A 65-year-old man presented with recurrent episodes of postural dizzin...